Is the Retinol-Binding Protein 4 a Possible Risk Factor for Cardiovascular Diseases in Obesity?
نویسندگان
چکیده
منابع مشابه
Retinol-binding protein 4 in human obesity.
Studies in mice suggest that adipocytes serve as glucose sensors and regulate systemic glucose metabolism through release of serum retinol-binding protein 4 (RBP4). This model has not been validated in humans. RBP4 was highly expressed in isolated mature human adipocytes and secreted by differentiating human adipocytes. In contrast to the animal data, RBP4 mRNA was downregulated in subcutaneous...
متن کاملObesity--a risk factor for cardiovascular diseases.
UNLABELLED Infantile and juvenile obesity is a medical, social and cultural problem, which reaches epidemic proportions worldwide. In Romania, according to the World Health Organization, one out of four Romanians is obese. As far as infantile obesity is concerned, Romania ranks third in Europe. Infantile obesity has a major impact on all body systems and is associated with risk factors for card...
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UNLABELLED Aims/Introduction: Visceral obesity has been suggested to be an independent risk factor for cardiovascular disease (CVD); the role of adipokines in the risk for CVD is less clear. Aim of this study was to investigate the relationship between parameters of visceral obesity and index of CVD risk factors. MATERIALS AND METHODS A cross-sectional analysis of healthy males (n = 116) a...
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BACKGROUND Retinol binding protein-4 (BP-4) a new adipocytokine, specifically binds to retinol, through experimental studies, reported its link between obesity and insulin resistance (IR). But till date no studies are available on influence of genetic predisposition of diabetes on RBP-4 expression. Hence, we aimed to study the influence of genetic predisposition of diabetes on the serum RBP-4 a...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21155229